Beat-to-beat determinants of the beat-to-beat temporal and spatial variability of repolarization
نویسندگان
چکیده
منابع مشابه
Beat-to-beat QT variability and cardiac autonomic regulation.
MODERN ELECTROCARDIOGRAPHIC (ECG) equipment allows easy collection of large volumes of digital signals. Their computer processing facilitates a number of ECG measurements that were previously unobtainable. Among such measurements, beat-to-beat QT interval variability has attracted some popularity and has been investigated in a variety of physiological and clinical conditions (3, 9, 11, 15–17, 2...
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Elevated ventricular repolarization lability is believed to be linked to the risk of ventricular tachycardia/ventricular fibrillation. However, ventricular repolarization is a complex electrical phenomenon, and abnormalities in ventricular repolarization are not completely understood. To evaluate repolarization lability, vectorcardiography (VCG) is an alternative approach where the electrocardi...
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Dynamic ventricular repolarization duration (VRD) and RR-interval coupling relates to autonomic control and myocardial electrical stability. Phase-rectification of RR-interval series separates acceleration (AC) and deceleration (DC) phases, reflecting sympathetic and parasympathetic influences on heart rate, respectively. To assess the effect of physical conditioning status on dynamic VRD and p...
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Single ventricular myocytes paced at a constant rate and held at a constant temperature exhibit beat-to-beat variations in action potential duration (APD). In this study we sought to quantify this variability, assess its mechanism, and determine its responsiveness to electrotonic interactions with another myocyte. Interbeat APD(90) (90% repolarization) of single cells was normally distributed. ...
متن کاملDeterminants of Beat-to-Beat Variability of Repolarization Duration in the Canine Ventricular Myocyte: A Computational Analysis
Beat-to-beat variability of repolarization duration (BVR) is an intrinsic characteristic of cardiac function and a better marker of proarrhythmia than repolarization prolongation alone. The ionic mechanisms underlying baseline BVR in physiological conditions, its rate dependence, and the factors contributing to increased BVR in pathologies remain incompletely understood. Here, we employed compu...
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ژورنال
عنوان ژورنال: Journal of Electrocardiology
سال: 2016
ISSN: 0022-0736
DOI: 10.1016/j.jelectrocard.2016.01.007